Krobo Edusei (26 December 1914 – 13 February 1984) was a Ghanaian politician and a member of Kwame Nkrumah's government. He was a popular, outspoken and prominent Ashanti activist galvanising support amongst the Ashantis for Nkrumah's independence movement. He served as Minister without Portfolio, Minister for Agriculture, Minister for Transport and Communication and Minister for the Interior under Nkrumah.